About Molecular Discovery Systems (MDSystems)

MDSystems was launched in 2006 with a focus on drug discovery and the validation of biomarkers for disease, therapy and diagnostics. The company’s primary investment is in:

HLS5 Tumor Suppressor Gene

The HLS5 tumour suppressor gene (HLS5) was reported by Professor Klinken’s team in 2004 at The West Australian Institute for Medical Research (WAIMR) led by Director Professor Peter Klinken.

Concerted research efforts previously undertaken reveal that HLS5 works through multiple pathways that may target cancer as well as a range of other diseases such as Huntington’s, Parkinson’s and HIV.

MDS has an extensive patent portfolio for HLS5 which encapsulates the gene both as a potential cancer therapeutic target and also underpinning its involvement in a variety of other diseases.

In recognition of its potential for detecting and treating cancer; outstanding organisations such as the National Health and Medical Research Council, the Cancer Council of WA, the National Breast Cancer Foundation, the Medical Research Foundation of Royal Perth Hospital and the Scott Kirkbride Melanoma Research Centre have awarded HLS5 research with high-priority funding.

MDS Papers

Research and Development Portfolio – Molecular Discovery Systems

Technique Article Dissociated flexor digitorum brevis myofibre culture system – A more mature muscle culture system is published by Wiley InterScience (R). 2007. The authors of the Cell Motility and the Cytoskeleton manuscript include: RAVENSCROFT, GIANINA; University of Western Australia, Physiology (School of Biomedical, Biomolecular and Chemical Sciences); University of Western Australia, WAIMR (Centre for Medical Research) Nowak, Kristen; Centre for Medical Research (University of WA), WAIMR Jackaman, Connie; Centre for Medical Research (University of WA), WAIMR Clement, Sophie; University of Geneva-CMU, Dept. of Clinical Pathology Lyons, Malcolm; Molecular Discovery Systems Gallagher, Samantha; Molecular Discovery Systems Bakker, Anthony; University of WA, Physiology (School of Biomedical, Biomolecular and Chemical Sciences) Laing, Nigel; Centre for Medical Research (University of WA), WAIMR. The abstract can be found at the Wiley InterScience site.